2P2I_DB Entries

2P2I_DB overall data statistics (as of 17 June 2020)

	Prot-Prot	Prot-Lig	Ligands	csv	sdf
All 2P2I_DB	32	996	880	2p2idb_all	2p2idb_all
Class 1	13	270	253	2p2idb_class-1	2p2idb_class-1
Class 2	8	191	173	2p2idb_class-2	2p2idb_class-2
Class BRD	11	535	454	2p2idb_class-3	2p2idb_class-3

Class 1
Family	Prot-Prot	Prot-Lig	Ligands	csv	sdf
Bcl2/Bax	2XA0	16	11	2p2idb_bcl2	2p2idb_bcl2
BclXL/Bak	1BXL	27	24	2p2idb_bclxl	2p2idb_bclxl
CIAP1-BIR3/CASPASE-9	3D9T	10	10	2p2idb_ciap2-bir3	2p2idb_ciap2-bir3
DCN1/UBC12	3TDU	8	8	2p2idb_dcn1	2p2idb_dcn1
HDM2/P53	1YCR	63	59	2p2idb_hdm2	2p2idb_hdm2
KEAP1/NRF2	2FLU	17	16	2p2idb_keap1	2p2idb_keap1
MDM4/P53	3DAB	10	10	2p2idb_mdm4	2p2idb_mdm4
Menin/MLL	4GQ6	28	29	2p2idb_menin	2p2idb_menin
MKEAP1/MNRF2	3WN7	14	14	2p2idb_mkeap1	2p2idb_mkeap1
WDR5/MLL1	4ESG	37	37	2p2idb_wdr5	2p2idb_wdr5
XDM2/P53	1YCQ	11	11	2p2idb_xdm2	2p2idb_xdm2
XIAP-BIR3/SMAC	1NW9	30	29	2p2idb_xiap-bir3	2p2idb_xiap-bir3
ZipA/FtsZ	1F47	4	4	2p2idb_zipa	2p2idb_zipa

Class 2
Family	Prot-Prot	Prot-Lig	Ligands	csv	sdf
HPV-E2/HPV-E1	1TUE	1	1	2p2idb_hpv-e2	2p2idb_hpv-e2
HRAS/SOS1	1BKD	4	3	2p2idb_hras	2p2idb_hras
IL-2/IL-2R	1Z92	7	7	2p2idb_il-2	2p2idb_il-2
Integrase/LEDGF	2B4J	83	72	2p2idb_integrase	2p2idb_integrase
KRAS/SOS1	KRAS	58	54	2p2idb_kras	2p2idb_kras
TNFA/TNFA	1TNF	4	4	2p2idb_tnfa	2p2idb_tnfa
TNFR1A/TNFB	1TNR	1	1	2p2idb_tnfr1a	2p2idb_tnfr1a
VHL/HIF1A	4AJY	33	32	2p2idb_vhl	2p2idb_vhl

Class BRD
Family	Prot-Prot	Prot-Lig	Ligands	csv	sdf
BAZ2B/H4	4QC3	59	52	2p2idb_baz2b	2p2idb_baz2b
BRD2-1/H4	2DVQ	22	22	2p2idb_brd2-1	2p2idb_brd2-1
BRD2-2/H4	2E3K	37	33	2p2idb_brd2-2	2p2idb_brd2-2
BRD3-1/H4	BD31	2	2	2p2idb_brd3-1	2p2idb_brd3-1
BRD3-2/H4	BD32	1	1	2p2idb_brd3-2	2p2idb_brd3-2
BRD4-1/H4	3UVW	276	263	2p2idb_brd4-1	2p2idb_brd4-1
BRD4-2/H4	BD42	28	27	2p2idb_brd4-2	2p2idb_brd4-2
BRD9/H4	4YY6	28	27	2p2idb_brd9	2p2idb_brd9
BRDT-1/H4	BDT1	4	4	2p2idb_brdt-1	2p2idb_brdt-1
CREBBP/H4	2RNY	65	64	2p2idb_crebbp	2p2idb_crebbp
PB1-5/H3	PB15	13	13	2p2idb_pb1-5	2p2idb_pb1-5

Basse MJ, Betzi S, Morelli X, Roche P: 2P2Idb v2: Update of a Structural Database Dedicated to Orthosteric Modulation of Protein-Protein Interactions. Database Update 2016; DOI: 10.1093/database/baw007
Basse MJ, Betzi S, Bourgeas R, Bouzidi S, Chetrit B, Hamon V, Morelli X, Roche P: 2P2Idb: A Structural Database Dedicated to Orthosteric Modulation of Protein-Protein Interactions. Nucleic Acid Research 2013; 41:D824-827. Pubmed ID: 23203891