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All families

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Class 2

Bromodomains

 

By Target

Class 1	Members	Class 2	Members	Bromodomains	Members
	Bcl2/Bax BclXL/Bak DCN1/UBC12 HDM2/P53 MDM4/P53 XDM2/P53 KEAP1/NRF2 MKEAP1/MNRF2 Menin/MLL WDR5/MLL WDR5-2/MYC CIAP1-BIR3/CASPASE-9 XIAP-BIR2/CASPASE-3 XIAP-BIR3/SMAC ZipA/FtsZ		HPV-E2/E1 HRAS/SOS1 KRAS/SOS1 IL-2/IL-2R Integrase/LEDGF TNFalpha TNFR1A/TNFB VHL/HIF1A		ATAD2/H4 BAZ2A/H4 BAZ2B/H4 BRD1/H4 BRD2-1/H4 BRD2-2/H4 BRD3-1/H4 BRD3-2/H3 BRD4-1/H4 BRD4-2/H4 BRDT-1/H4 BRDT-2/H4 BRPF1/H4 BRD7/H4 BRD9/H4 CECR2/H4 CREBBP/H4 EP300/H4 FALZ/H4 GCN5L2/H4 KIAA1240/H4 PB1-2/H3 PB1-5/H4 PCAF/H4 PHIP-2/H4 SMARCA2/H4 SMARCA4/H4 TAF1-1/H4 TAF1-2/H4 TAF1L-2/H4 TRIM24/H4

 

 

2P2Idb v2: Update of a Structural Database Dedicated to Orthosteric Modulation of Protein-Protein Interactions Basse MJ, Betzi S, Morelli X, Roche P. Database update 2016. DOI : 10.1093/database/baw007

   2P2Idb: A Structural Database Dedicated to Orthosteric Modulation of Protein-Protein Interactions Basse MJ, Betzi S, Bourgeas R, Bouzidi S, Chetrit B, Hamon V, Morelli X, Roche P. Nucleic Acid Research 2013; 41:D824-827. Pubmed ID: 23203891